What are the requirements for parenteral preparation?

The parenteral preparations should be free from all types of micro – organisms. An aseptic conditions are required to be maintained during the preparation of Parenteral products and its administration. The parenteral product must pass the test of Sterility.

What are the three critical requirements for parenteral solutions?

They must meet the following minimum com-pendia criteria: To be sterile and pyrogen-free. To be clear or practically exempt of visible particle and to be free from sub-visible particles as required by pharmacopeias EP, USP and JP.

Which are the oily solvents used for parenteral?

21 NON – AQUEOUS VEHICLES Fixed oils (vegitable origin, liquid, and rancid resistance ,unsaturated, free fatty acid content ) Peanut oil Corn oil Cotton seed oil (depo-testosterone) Sesame oil Soyabean oil Ethyl oleate Isopropyl myristate. 22. 22 ANTIBACTERIAL AGENTS These are added in multiple dose containers.

What should the salient features of parenteral products?

Parenteral products are unique from any other type of pharmaceutical dosage form for the following reasons: • All products must be sterile. All products must be free from pyrogenic (endotoxin) contamination. Injectable solutions must be free from visible particulate matter. This includes reconstituted sterile powders.

How are parenteral preparations evaluated?

 There are mainly seven quality control tests for parenterals are performed :  Leaker test  Pyrogen test  Particulate test  Sterility test  Clarity test.  Closure integrity test  Weight variation test or content uniformity test. …  Leaker test for ampoules is intended to detect incompletely sealed ampoules.

What are types of parenteral formulation?

Parenteral preparations include solutions, suspensions, emulsions, powders, and gels.

What are the three main components of TPN?

TPN is a mixture of separate components which contain lipid emulsions, dextrose, amino acids, vitamins, electrolytes, minerals, and trace elements. [7][8] TPN composition should be adjusted to fulfill individual patients' needs. The main three macronutrients are lipids emulsions, proteins, and dextrose.